Fun, arcade-style game to educate students about drug effects and potential harms. Short introduction to the effects of cannabis, LSD, cocaine, MDMA/ecstasy, and heroin. The increasing use of the darknet to buy MDMA (and other drugs), and the embrace of harm reduction services such as drug safety checking, are clear indicators of thi A study conducted by 10 drug-checking organisations from the TEDI network found that the increase in MDMA content in tablets in this time period was directly related to an increase in the average weight of ecstasy tablets (Vrolijk et al., 2022). The average content of MDMA in ecstasy tablets appears to be on a slight downward trend from 2019, after close to a decade of increasingly stronger (and larger) tablets becoming available on the market. On occasion, neurotoxic compounds such as PMMA (5) are detected mixed with, or as a replacement for, MDMA in ecstasy tablets. From 2019 onwards a new cycle appears to have begun, whereby the number of ecstasy tablets containing other substances alongside, or instead of, MDMA has increased (as expressed by a drop in percentage in the indexed trends shown above from 96 % in 2019 to 73 % in 2022). Crystal MDMA was marketed as a purer product compared to ecstasy tablets, an assertion that was and remains largely true (see Section The trend of large tablets containing more MDMA may be reversing). One way to observe these cycles is to monitor rates of adulteration, as expressed by the percentage of tested samples of seized ecstasy tablets that contain MDMA and no other click to investigate scheduled substances. Wastewater-based methods (1) The European Web Survey on Drugs (EWSD) is a voluntary, anonymous survey run by the EUDA and its partners targeting directly people who use drugs who are 18 years old or older, and are living in one of the participating countries. When using wastewater data to estimate MDMA markets, the use of MDMA is based on the excreted parent drug, rather than on an excreted metabolite (which is the case for some other drugs, such as cocaine and heroin). While a slight decrease in price was observed in 2022 for ecstasy tablets, this may not be statistically significant or sustained in the coming years. In fact, it could be argued that MDMA in the form of ecstasy tablets became cheaper between 2012 and 2019 as tablets containing larger quantities of MDMA became increasingly available on the market (see Section The trend of large tablets containing more MDMA may be reversing). Increased ener 3,4-Methyl​enedioxy​methamphetamine or more commonly known as Ecstasy (E), it is a psychoactive drug. For over 200 years we have designed and delivered services that build resilience and aspiration in people and communities. Together, we tackle the pressing issues in public services. Catch22 [[https://royalmedspharma.com/product/ecstasy-pills-for-sale/|click to investigate]] designs and delivers services that build resilience and aspiration in people of all ages and within communities across the UK. Ecstasy adulteration is responsive to market pressures However, these data are not generalisable either, and as such should be interpreted with caution. These products typically contain MDMA hydrochloride (see Box Forms of MDMA present on the European market). According to 2021 data, tablets and powders/crystals share the EU MDMA market equally, with some variability among countries in terms of preference for either ecstasy tablets or MDMA powders/crystals click to investigate (see Figure 6.1. Distribution of usual MDMA forms across countries). Analysis of drugs sold as MDMA/ecstasy in Australia shows that these contain a wide range of substances, and some contain no MDMA at all. Vendors in the Netherlands appear to be developing a fairly successful international trade of ecstasy-type drugs and stimulants from cryptomarkets, but it appears that most countries are selling illicit drugs within domestic borders. Three quarters of all Dutch revenues from illicit drugs sold on cryptomarkets were from two drug categories — ecstasy-type drugs and stimulants. In the Netherlands, in 2022, the price of 1 kilogram of (locally produced) MDMA crystals was reported at EUR 2 300, whereas 1 litre of MDMA oil (which can be converted into crystals or powder, and subsequently ecstasy tablets) was reported at EUR per litr Based on reporting from drug-checking clients, the majority of samples were reported as being obtained from a supplier (either a trusted supplier or a random street supplier) and a smaller proportion (close to 5 %) as bought on the internet (surface web or darknet Where prevalence is higher, it may suggest that MDMA is no longer a niche or subcultural drug limited to dance clubs and parties in those markets. According to survey data, the two largest MDMA consumer markets per capita in the European Union are the Netherlands and Ireland, with 6 % or more click to investigate people aged 15 to 34 reporting to have consumed MDMA in the last year. Some of the high-strength ecstasy tablets are scored to allow consumers to divide them into smaller portions.